Paul Sutton

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New method uses AI to design artificial proteins

New method uses AI to design artificial proteins

This research is related to the 2024 Nobel Prize in chemistry. Using AI to design proteins.

Protein design aims to create customized antibodies for therapies, biosensors for diagnostics, or enzymes for chemical reactions. An international research team has now developed a method for designing large new proteins better than before and producing them with the desired properties in the laboratory.

Links

Tags

#Science,#Chemistry,#BioChemistry,#AI,#Protein,#ProteinFolding, #Design,#Medicine,#NobelPrize


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Death of critical thinking

Great piece of writing, looks at how we have changed our approach to critical thinking and how this impacts on our ability to read, comprehend information so we can understand facts. The ability to read and comprehend is important in a world of misinformation,

Tags

#Reading,#CriticalThinking


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ISS Passes

The International Space Station is visible this week, details of visible passes for South Devon can be found on the Heavens Above website. You will need to adjust the settings, but if you are in South Devon you should be able to get details for your location.


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RISC-V Emulator

While I am mostly interested in science, I think this sort of thing is worth sharing, as these devices are probably really useful for building devices that can help with scientific research.

The pine64 devices include some that are powered by the RISCV processor, which I have made posts about before. It is now possible to emulate one of the processors so that projects can be developed without having direct access to the hardware (this is how I understand this). You can read about the Sophgo SG2000 SoC (Pine64 Oz64 / Milk-V Duo S)

Links

Tags

#RISCV,#RISC-V,#Pine,#Pine64,


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Hunting the Stellar Undead

The next stsci lecture is Hunting the Stellar Undead and will take place on Tuesday 3rd December 2024.

Please see the lecture page for more information.

Tags

#STSCI,#Lecutre,#Public


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Black Hole Tears Star to Shreds, Unleashing Cosmic Shockwaves

Black Hole Tears Star to Shreds, Unleashing Cosmic Shockwaves

This is interesting, I will add a link to NICER (see article) to the links page.

Black holes seem really complex, and there is probably much more to learn. It is also worth watching the two videos as a further explainer to the research and the resulting paper.

So this is looking at a black hole, and how it is interacting with a local star trapped within its gravitational pull, As the star is pulled apart, some of the matter becomes a disk around the black hole, however this matter is then also interacting with another star.

If I understand the paper or at least article, this event links tidal disruption events * and quasi-periodic eruptions, helping astronomers understand black hole environments and shape future research

  • The above link is to Wikipedia, as this is NOT an academic source of information, please use a different source, link is for reference only

On an unrelated note, according to the Solar System series by Professor Brian COX, Rings have formed around planets when an object such as an asteroid gets caught in the gravitational pull of the planet, Moons are also objects that have been caught up.

I am not sure if the two phenomenons are related in that stars being ripped apart by a black hole are a similar event, just on a much larger scale.

According to MIT there have been other similar events detailed here

Links

Tags

#Science,#Astronomy.#Physics,#AstroPhysics,#BlackHole


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Old LibreOffice versions

From time to time there is a requirement to download older versions of LibreOffice, for example it could be as part of a retro computing project where an older Windows OS is being used.

The main LibreOffice archive is at

So for example I have downloaded version 5.4.7.2, which can be found at https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2

There is a really basic bash script to download which I have modified so it works better and also has some extra wget commands in to download additional resources.

mkdir LibreOffice_All_Platforms
cd LibreOffice_All_Platforms

# Array of download URLs for LibreOffice 5.4.7.2 installers

# Array of download URLs for LibreOffice 5.4.7.2 full package (all files)
urls=(
  # Windows Installers
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86/LibreOffice_5.4.7.2_Win_x86.msi"
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86_64/LibreOffice_5.4.7.2_Win_x64.msi"
    # Help packs for 32 and 64 bit windows

"https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86/LibreOffice_5.4.7.2_Win_x86_helppack_en-GB.msi"
"https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86/LibreOffice_5.4.7.2_Win_x86_helppack_en-GB.msi.asc"
"https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86_64/LibreOffice_5.4.7.2_Win_x64_helppack_en-GB.msi"
"https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86_64/LibreOffice_5.4.7.2_Win_x64_helppack_en-GB.msi.asc"
"https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86/LibreOffice_5.4.7.2_Win_x86_helppack_en-GB.msi"
"https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86/LibreOffice_5.4.7.2_Win_x86_helppack_en-US.msi.asc"

  
  # macOS Installer
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/mac/x86_64/LibreOffice_5.4.7.2_MacOS_x86-64.dmg"
  
  # Linux DEB Packages
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/deb/x86/LibreOffice_5.4.7.2_Linux_x86_deb.tar.gz"
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/deb/x86_64/LibreOffice_5.4.7.2_Linux_x86-64_deb.tar.gz"
  
  # Linux RPM Packages
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/rpm/x86/LibreOffice_5.4.7.2_Linux_x86_rpm.tar.gz"
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/rpm/x86_64/LibreOffice_5.4.7.2_Linux_x86-64_rpm.tar.gz"
  
  # Language Packs for Windows
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86/LibreOffice_5.4.7.2_Win_x86_langpack.msi"
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86_64/LibreOffice_5.4.7.2_Win_x64_langpack.msi"
  
  # Language Packs for macOS
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/mac/x86_64/LibreOffice_5.4.7.2_MacOS_x86-64_langpack.dmg"
  
  # Language Packs for Linux DEB
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/deb/x86/LibreOffice_5.4.7.2_Linux_x86_deb_langpack.tar.gz"
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/deb/x86_64/LibreOffice_5.4.7.2_Linux_x86-64_deb_langpack.tar.gz"
  
  # Language Packs for Linux RPM
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/rpm/x86/LibreOffice_5.4.7.2_Linux_x86_rpm_langpack.tar.gz"
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/rpm/x86_64/LibreOffice_5.4.7.2_Linux_x86-64_rpm_langpack.tar.gz"
  
  # SDK (Software Development Kit)
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/deb/x86_64/LibreOffice_5.4.7.2_Linux_x86-64_deb_sdk.tar.gz"
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/rpm/x86_64/LibreOffice_5.4.7.2_Linux_x86-64_rpm_sdk.tar.gz"
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86/LibreOffice_5.4.7.2_Win_x86_sdk.msi"
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86_64/LibreOffice_5.4.7.2_Win_x64_sdk.msi"
  
  # Source Files
  "https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/src/libreoffice-5.4.7.2.tar.xz"
)

# Loop to download each file
for url in "${urls[@]}"; do
  wget "$url"
done

# extra to be added to the above script

The following additional commands to download helppacks are:


wget -c https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86/LibreOffice_5.4.7.2_Win_x86_helppack_en-GB.msi
wget -c https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86/LibreOffice_5.4.7.2_Win_x86_helppack_en-GB.msi.asc
wget -c https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86_64/LibreOffice_5.4.7.2_Win_x64_helppack_en-GB.msi
wget -c https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86_64/LibreOffice_5.4.7.2_Win_x64_helppack_en-GB.msi.asc
wget -c https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86/LibreOffice_5.4.7.2_Win_x86_helppack_en-GB.msi
wget -c https://downloadarchive.documentfoundation.org/libreoffice/old/5.4.7.2/win/x86/LibreOffice_5.4.7.2_Win_x86_helppack_en-US.msi.asc

These could be integrated in to the above script.

Powershell

If you are using Windows, then you may want to use powershell for this. You will need to set up both an array then use a loop to read each item in the array and pass this to wget.

Maybe a good starting point.


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Celebrating disabled scientists

Another infographic from Compound Interest

Celebrating disabled scientists

Other links

Tags

#Science,#Scientists,#Disabled


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Aurora Colours

Another infographic from Compound Interest

Aurora Colours

Other links

Tags

#Aurora,#Colours


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Prof Brian Cox – Solar System

The fantastic 5 part series on the Solar System, presented by Professor Brian Cox is now up on BBC iPlayer if you would like to catch up

Series 1: 1. Volcano Worlds Professor Brian Cox explores planets and moons erupting with fire and ice. 59 mins Series 1: 2. Dark Worlds Professor Brian Cox goes on a journey to the least explored regions of the solar system. 59 mins Series 1: 3. Storm Worlds Professor Brian Cox explores the wildest weather across the solar system. 59 mins Series 1: 4. Ice Worlds Professor Brian Cox goes on a journey to the icy, frozen worlds of the solar system. 59 mins Series 1: 5. Strange Worlds


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